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The Korean Journal of Medicine 2011;80(2): 121-125.
담도암과 감별이 어려웠던 국소형 자가면역성 췌장염
장영주1, 양기영1, 김상범2, 박선후3, 안영1, 양재현1, 이종환1
Focal-Type Autoimmune Pancreatitis Mimicking Cholangiocarcinoma
Young Joo Jang1, Ki Young Yang1, Sang Bum Kim2, Sun Hoo Park3, Young Ahn1, Jae Hyun Yang1, Jong Hwan Lee1
ABSTRACT
Autoimmune pancreatitis (AIP) is a rare pancreatic disorder of autoimmune etiology. It has characteristic clinical features, such as pancreatic parenchymal swelling and irregular narrowing of the main pancreatic duct due to plasma cell infiltration. It occurs mostly in Far East Asia. Although it generally involves whole pancreatic parenchyma, some cases demonstrate focal involvement of the pancreas or adjacent organs, which are often mistaken for cancer. We report a case of AIP that was confused with cholangiocarcinoma of the distal common bile duct (CBD). The patient experienced sudden development of jaundice with vague abdominal discomfort. Abdominal computed tomography revealed a well-enhanced lesion, and positron emission tomography showed high standard uptake value at the distal CBD, indicating malignant disease. However, pathological examination by surgical excision indicated focal-type AIP. This is believed to be the first case of focal-type AIP mimicking cholangiocarcinoma.
Keywords: Autoimmunity; Pancreatitis; Cholangiocarcinoma
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