Korean J Med > Volume 77(6); 2009 > Article
The Korean Journal of Medicine 2009;77(6):750-754.
Four cases of autoimmune cholangitis
Seung Kyu Chung, Jae Young Jang, Soung Won Jeong, Chan-Sup Shim, Boo-Sung Kim, Yoon-Mi Jeen, So Young Jin
자가면역성 담관염 4예
정승규, 장재영, 정승원, 심찬섭, 김부성, 진윤미, 진소영
Abstract
Autoimmune cholangitis is a disease with clinicopathologic features of primary biliary cirrhosis without antimitochondrial antibodies and, frequently, with high antinuclear antibody titers. Alternative terms have been suggested, including antimitochondrial antibody-negative primary biliary cirrhosis, immunocholangitis, autoimmune cholangiopathy, and autoimmune hepatobiliary overlap syndrome type 1. The question of whether autoimmune cholangitis is distinct from primary biliary cirrhosis and autoimmune hepatitis or is an antimitochondrial antibody-negative variant of primary biliary cirrhosis and autoimmune hepatitis is controversial. This case report describes the clinical, immunohistochemical, and pathological findings in four patients with autoimmune cholangitis and reviews the literature.
Key Words: Autoimmune hepatitis; Primary biliary cirrhosis


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