Korean J Med > Volume 77(5); 2009 > Article
The Korean Journal of Medicine 2009;77(5):1142-1147.
A case of brain metastasis from scirrhous type hepatocellular carcinoma
Sang Ock Kim, Hee Kyung Baek, Do Kyong Kim, Bong Chul Shin, Jin Sook Jeong, Sang Young Han, Sung Wook Lee
뇌종양의 증상 발현으로 진단된 경화형 간세포암 1예
김상옥·백희경·김도경·신봉철·정진숙·한상영·이성욱, Hee Kyung Baek, Do Kyong Kim, Bong Chul Shin, Jin Sook Jeong, Sang Young Han, Sung Wook Lee
Abstract
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in far eastern countries. Extrahepatic metastases develop in 64% of patients with HCC. Lung, regional lymph node, bone, and adrenal gland are common sites of HCC metastasis, while metastases to the brain and skull are rare. Recently, the survival rate of HCC has increased with the development of new treatment modalities, and this has led to a higher frequency of HCC brain metastasis. However, no reports have mentioned the relationship between the subtype of HCC and clinical course. We report a case of scirrhous type HCC, presenting with the manifestations of an intracranial mass lesion with no symptoms or signs suggestive of HCC. We excised the intracranial metastatic mass and then treated the patient with palliative chemotherapy and radiotherapy. The patient survived for over 10 months. (Korean J Med 77:S1142-S1147, 2009)
Key Words: Carcinoma, hepatocellular; Neoplasm; Metastasis; Brain cancer; Carcinoma, scirrhous


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