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Korean J Med > Volume 88(2); 2015 > Article
The Korean Journal of Medicine 2015;88(2): 202-206.
간세포암종에서 발생한 공동 형태의 폐 전이
조용숙, 배원, 김주혜, 이하연, 곽낙원, 고성준, 이창훈
서울대학교 의과대학 서울대학교병원 호흡기내과
Cavitary Form of Lung Metastasis from Advanced Hepatocellular Carcinoma
Yong Suk Jo, Won Bae, Joo Hae Kim, Ha Youn Lee, Nak Won Kwak, Sung Jun Ko, Chang-Hoon Lee
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Chang-Hoon Lee ,Tel: +82-2-2072-4743, Fax: +82-2-762-9662, Email: kauri670@gmail.com
Received: June 17, 2014;   Revised: July 22, 2014;   Accepted: August 28, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The most common site of extrahepatic metastasis in cases of advanced hepatocellular carcinoma is the lung. A 60-year-old Korean male had been previously diagnosed with hepatocellular carcinoma and was treated several times with transcatheter arterial chemoembolization prior to a regime of sorafenib after multiple bone metastases were detected. Despite 2 months of systemic treatment, the disease progressed, and newly developed cavitary nodules and ground glass opacities were observed on a chest computed tomography scan. Initially the patient was diagnosed with septic pneumonia and was subsequently treated with antibiotics over 2 weeks, with no observable improvement. A percutaneous transthoracic needle aspiration biopsy was performed to ascertain the noninfectious origin of the lung lesions. As a result, a rare form of pulmonary metastasis from hepatocellular carcinoma was discovered. Unfortunately, there were no available treatment options for the patient and so end-of-life care was recommended.
Keywords: Hepatocellular carcinoma; Infection; Metastasis
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