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The Korean Journal of Medicine 2009;77(4): 517-521.
신증후군 환자에서 발생한 뇌정맥혈전증 1예
김현정, 정덕은, 변승재, 이유민, 이지은, 안선호, 송주흥
Cerebral sinovenous thrombosis associated with nephrotic syndrome
Hyun Jung Kim, Duk Eun Jung, Seung Jae Byun, Yu Min Lee, Ji Eun Lee, Seon Ho Ahn, Ju Hung Song
Nephrotic syndrome is associated with proteinuria, hypoalbuminemia, edema, hyperlipidemia, and thromboembolic complications. Thromboembolic complications of nephrotic syndrome are common, especially in the renal vein, while cerebral venous thrombosis is a less frequent complication of minimal change nephrotic syndrome. The pathophysiology remains unclear, but various changes in coagulant and anticoagulant factors may be responsible. We report a case of cerebral venous thrombosis associated with nephrotic syndrome. A 19-year-old man was admitted with a headache and nausea. Cerebral thrombosis was diagnosed on brain computed tomography and magnetic resonance imaging. He recovered gradually after treatment with anticoagulants and achieved control of the nephrotic syndrome. A discussion of this case, coupled with a review of the literature, emphasizes that an early diagnosis is essential for anticoagulation therapy and a successful outcome. (Korean J Med 77:517-521, 2009)
Keywords: Cerebral thrombosis; Nephrotic syndrome
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