Cerebral sinovenous thrombosis associated with nephrotic syndrome |
Hyun Jung Kim, Duk Eun Jung, Seung Jae Byun, Yu Min Lee, Ji Eun Lee, Seon Ho Ahn, Ju Hung Song |
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신증후군 환자에서 발생한 뇌정맥혈전증 1예 |
김현정, 정덕은, 변승재, 이유민, 이지은, 안선호, 송주흥 |
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Abstract |
Nephrotic syndrome is associated with proteinuria, hypoalbuminemia, edema, hyperlipidemia, and thromboembolic complications.
Thromboembolic complications of nephrotic syndrome are common, especially in the renal vein, while cerebral venous
thrombosis is a less frequent complication of minimal change nephrotic syndrome. The pathophysiology remains unclear, but various
changes in coagulant and anticoagulant factors may be responsible. We report a case of cerebral venous thrombosis associated
with nephrotic syndrome. A 19-year-old man was admitted with a headache and nausea. Cerebral thrombosis was diagnosed on
brain computed tomography and magnetic resonance imaging. He recovered gradually after treatment with anticoagulants and achieved
control of the nephrotic syndrome. A discussion of this case, coupled with a review of the literature, emphasizes that an early
diagnosis is essential for anticoagulation therapy and a successful outcome. (Korean J Med 77:517-521, 2009) |
Key Words:
Cerebral thrombosis; Nephrotic syndrome |
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