| A case of signet ring cell gastric carcinoma initially presenting with disseminated bone marrow metastases |
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Hwa Mock Kim, Jung Ho Park, Hyun Suk Kim, Ji Hoon Choi, Chang Joon Kim, Eun A Lee |
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| 증례 : 파종성 골수 전이를 통해 발견된 반지세포 위암 1예 |
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김화목.박정호.김현석.최지훈.김창준.이은아 , Jung Ho Park, Hyun Suk Kim, Ji Hoon Choi, Chang Joon Kim, Eun A Lee |
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| Abstract |
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Bone metastases from gastric carcinoma are reported in up to 17% of cases. However, disseminated bone metastasis is very rarely the first symptom of gastric carcinoma.
We present a 63-year-old male who had disseminated bone metastases as a symptom of signet ring cell gastric carcinoma. He came to the clinic complaining of back pain and dizziness that had started 6 months earlier. Blood tests showed pancytopenia, and the alkaline phosphatase (ALP) was elevated 10 times higher than normal.
Magnetic resonance imaging of the thoracic and lumbar spine and the entire skeleton was subsequently performed, and severe bone marrow infiltration was found. A bone marrow biopsy showed metastatic infiltration of signet-ring-shaped carcinoma. We performed positron emission tomography to find the primary site, and hypermetabolism on the stomach wall implied that the primary site was the stomach. (Korean J Med 75:S787-S791, 2008) |
| Key Words:
Signet ring cell carcinoma; Bone marrow; Metastasis |
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