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The Korean Journal of Medicine 2007;72(2): 274-249.
증례 : 폐 유암종을 동반한 제1형 다발성 내분비 선종증 1예
김상윤
A case of multiple endocrine neoplasia type 1 with a bronchial carcinoid tumor
Sang Yoon Kim
고려대학교 의과대학 내과학교실
ABSTRACT
Approximately, one third of patients with gastrinoma have multiple endocrine neoplasia type 1 (MEN 1). But bronchial carcinoid tumors occur infrequently and the natural courses of them remain unclear. Recently the somatostatin receptor scintigraphy was reported to be more sensitive than any other tumor-localization methods. A 62 years old woman had multiple ulcers in duodenum. Her gastin level was markedly elevated. She not only was confirmed to have islet cell tumor in pancreatic head portion with involvement of intra-abdominal lymph node but also was confirmed to have endocrine tumor in the right lower lung through computed tomography and somatostatin receptor scintigraphy. Then, we found that she had parathyroid adenoma and pituitary prolactinoma. Genetic analysis of DNA revealed a nonsense mutation in the MEN 1 gene. We reported this case with a review of the literature because this is the first report of bronchial carcinoid with MEN 1 in Korea.(Korean J Med 72:S244-S249, 2007) Key Words : Multiple endocrine neoplasia type 1, Carcinoid tumor
Keywords: Multiple endocrine neoplasia type 1, Carcinoid tumor
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