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Korean J Med > Volume 88(3); 2015 > Article
The Korean Journal of Medicine 2015;88(3): 313-317.
갑상선전절제술을 받은 환자에서 급성 Levothyroxine 중독 1예
정윤, 안희정, 현진수, 장회수, 김진화, 김상용
조선대학교 의과대학 조선대학교병원 내분비대사내과
A Case of Massive Levothyroxine Intoxication in a Patient with Total Thyroidectomy
Yun Jung, Hee Jung Ahn, Jin Soo Hyun, Hoe Soo Jang, Jin Hwa Kim, Sang Yong Kim
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chosun University Hospital, School of Medicine, Chosun University, Gwangju, Korea
Corresponding Author: Jin Hwa Kim ,Tel: +82-62-220-3011, Fax: +82-62-223-3316, Email: endocrine@chosun.ac.kr
Received: April 23, 2014;   Revised: July 30, 2014;   Accepted: August 18, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The use of levothyroxine is increasingly widespread. There are relatively few reports of acute massive levothyroxine intoxication leading to emergencies in adults, and such intoxication has a wide range of presentations. Although thyroid gland activity is suppressed by thyroid stimulating hormone as a result of overdose exposure to exogenous thyroid hormone, it is unclear what symptoms are to be expected in acute levothyroxine intoxication in the absence of the thyroid gland. We report a case of massive acute levothyroxine intoxication in a patient with total thyroidectomy, along with observed changes over time in thyroid hormone levels and symptoms. To the best of our knowledge, this report presents the first description of acute massive levothyroxine intoxication in the absence of a thyroid gland.
Keywords: Levothyroxine; Intoxication; Total thyroidectomy
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