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The Korean Journal of Medicine 2007;72(2): 256-260.
利앸 : 留먮떒鍮꾨利앷낵 遺媛묒긽꽑 꽑醫낆씠 룞諛섎맂 젣 1삎 떎諛쒖꽦 궡遺꾨퉬꽑醫 1삁
씠遺湲
A case of multiple endocrine neoplasia type 1 with acromegaly and a parathyroid adenoma
Bu Ghil Lee
怨좊젮븰援 쓽怨쇰븰 궡怨쇳븰援먯떎
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ABSTRACT
Multiple endocrine neoplasia type 1 (MEN 1) is an inherited autosomal dominant tumor syndrome, characterized by a heterogeneous association of neoplasms that originate from the parathyroid gland, endocrine pancreas, and anterior pituitary gland. A fifty three year old woman was admitted due to acromegalic features. She was diagnosed with acromegaly of the pituitary gland tumor determined by elevated insulin-like growth factor-1 (IGF-1) and sellar magnetic resonance imaging. The patient was treated with a trans-sphenoidal adenomaectomy and post-operative radiotherapy. During follow up periods, hypercalcemia was detected and also intact parathyroid hormone (PTH) was elevated. On a neck ultrasound, computerized tomography, and parathyroid scan (201T1-99mTc), a parathyroid mass lesion was found in the left lower pole of the parathyroid gland. We report a case of MEN type 1, who was shown to have a pituitary adenoma and a parathyroid adenoma, with a review of literature..(Korean J Med 72:S256-S260, 2007) Key Words : Multiple endocrine neoplasia type 1 (MEN 1), Acromegaly, Parathyroid adenoma
Keywords: Multiple endocrine neoplasia type 1 (MEN 1), Acromegaly, Parathyroid adenoma
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