| A case of multiple endocrine neoplasia type 1 with acromegaly and a parathyroid adenoma |
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고려대학교 의과대학 내과학교실 |
| 증례 : 말단비대증과 부갑상선 선종이 동반된 제 1형 다발성 내분비선종 1예 |
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이부길 |
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| Abstract |
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Multiple endocrine neoplasia type 1 (MEN 1) is an inherited autosomal dominant tumor syndrome, characterized by a heterogeneous association of neoplasms that originate from the parathyroid gland, endocrine pancreas, and anterior pituitary gland. A fifty three year old woman was admitted due to acromegalic features. She was diagnosed with acromegaly of the pituitary gland tumor determined by elevated insulin-like growth factor-1 (IGF-1) and sellar magnetic resonance imaging. The patient was treated with a trans-sphenoidal adenomaectomy and post-operative radiotherapy.
During follow up periods, hypercalcemia was detected and also intact parathyroid hormone (PTH) was elevated. On a neck ultrasound, computerized tomography, and parathyroid scan (201T1-99mTc), a parathyroid mass lesion was found in the left lower pole of the parathyroid gland. We report a case of MEN type 1, who was shown to have a pituitary adenoma and a parathyroid adenoma, with a review of literature..(Korean J Med 72:S256-S260, 2007)
Key Words : Multiple endocrine neoplasia type 1 (MEN 1), Acromegaly, Parathyroid adenoma |
| Key Words:
Multiple endocrine neoplasia type 1 (MEN 1), Acromegaly, Parathyroid adenoma |
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