A case of idiopathic hypereosinophilic syndrome manifested by prosthetic aortic valve dysfunction

Tae Hyuck Choi,; Juyong Lee,; Sang-Sig Cheong,; Yoon-Suck Choi,; Hyun Il Hong,; Chong Bin Park,; Gil Hyun Kang,

Korean J Med > Volume 69(3); 2005 > Article

Original Article

The Korean Journal of Medicine 2005;69(3):974-978.

A case of idiopathic hypereosinophilic syndrome manifested by prosthetic aortic valve dysfunction

Tae Hyuck Choi, Juyong Lee, Sang-Sig Cheong, Yoon-Suck Choi, Hyun Il Hong, Chong Bin Park, Gil Hyun Kang

Department of Medicine, Sungkyunkwan University School of Medicine

증례 : 인공 대동맥 판막 기능 부전으로 나타난 과호산구 증후군 1예

최태혁&#;이주용&#;정상식&#;최윤석&#;홍현일&#;박종빈&#;강길현, Juyong Lee, Sang-Sig Cheong, Yoon-Suck Choi, Hyun Il Hong, Chong Bin Park, Gil Hyun Kang

Abstract

Idiopathic hypereosinophilic syndrome (HES) refers to a group of leukoproliferative disorders characterized by unexplained persistent eosinophilia associated with damage to several organ. Cardiac involvement is the major source of morbidity and mortality. There have been several case reports that showed various types of cardiac involvement including native or prosthetic valve dysfunction with this syndrome. However, there has been no report involved mechanical aortic valve. We, for the first time, report a case of a 58-year-old man with idiopathic hypereosinophilic syndrome manifested by prosthetic mechanical aortic valve dysfunction that was successfully treated by valvular replacement, steroid and hydroxyurea therapy.(Korean J Med 69:S974-S978, 2005)

Key Words: Hypereosinophilic syndrome, Valvular heart disease