| A case of the ankylosing spondylitis presented with Henoch-Schönlein purpura |
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Kyung Hee Ryu, Yun Tae Chae, Eun Hyang Ko, Jae Hyun Moon, Sung Kwan Hong, Jeong Yun Shim, Seung-Jae Hong |
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Department of Medicine, Sungkyunkwan University School of Medicine |
| 증례 : Henoch-Schönlein 자색반증을 동반한 강직성 척추염 1예 |
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류경희&#;채윤태&#;고은향&#;문재현&#;홍성관&#;심정연&#;홍승재, Yun Tae Chae, Eun Hyang Ko, Jae Hyun Moon, Sung Kwan Hong, Jeong Yun Shim, Seung-Jae Hong |
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| Abstract |
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Cutaneous leucocytoclastic vasculitis in patients with ankylosing spondylitis is rarely reported. Such an association might not be coincidental, as serum immunoglobulin A (Ig A) levels are reported to be high during the active inflammatory phases of ankylosing spondylitis and cutaneous leucocytoclastic vasculitis. But this finding supports the concept of abnormal Ig A immune stimulation in pathogenesis of ankylosing spondylitis and cutaneous leucocytoclastic vasculitis.
We report a 17 year-old male patient with ankylosing spondylitis accompanying with H-S purpura who initially presented with fever, abdominal pain, swelling and palpable pur-pura. Cutaneous biopsy showed neutrophilic infiltration of blood vessel wall with marked leukocytoclasia and fibrinoid necrosis of dermal vessels with extravased erythrocytes. The purpuric rash disappeared in one month without specific treatment. The patient was treated with indometacin and Sulfasalazine.(Korean J Med 69:S959-S963, 2005) |
| Key Words:
Ankylosing spondylitis, Cutaneous leucocytoclastic vasculitis, Immuno-globulin A (IgA) |
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