| A case of adrenocortical insufficiency associated with bilateral adrenal metastasis of non-small cell lung cancer |
|
Jue Yong Lee, Seung Jin Kong, Man Jo Jeon, Seong Jin Lee, Hun Ho Song, Moon Gi Choi, Myung Goo Lee |
|
Department of Medicine, Sungkyunkwan University School of Medicine |
| 증례 : 양측 부신 전이를 동반한 비소세포폐암에서 발현된 부신피질기능저하증 1예 |
|
이주용&#;공승진&#;전만조&#;이성진&#;송헌호&#;최문기&#;이명구, Seung Jin Kong, Man Jo Jeon, Seong Jin Lee, Hun Ho Song, Moon Gi Choi, Myung Goo Lee |
|
|
|
|
|
|
| Abstract |
|
Metastatic tumor is the most common malignancy in adrenal glands, and high occurrence of adrenal metastasis is closely related to its rich sinusoidal blood supply. Lung is common origin of metastatic tumor, and 42% of non-small cell lung cancer is associated with metastasis to adrenal glands. In spite of high incidence of adrenal metastasis, metastatic tumor very rarely causes adrenocortical insufficiency possibly because adrenal cortex must be almost completely destroyed before development of adrenocortical insufficiency. Symptoms of adrenocortical insufficiency such as fatigue, generalized weakness, anorexia, nausea, vomiting, abdominal pain are usually nonspecific, and insidiously occur. In addition, these symptoms are often overlooked or misdiagnosed as symptoms of cancer progression, thereby adrencortical insufficiency is not properly managed. We report a 68-year-old man who presented with nonspecific symptoms, and was diagnosed as adrenocortical insufficiency associated with bilateral adrenal metastasis of non-small cell lung cancer by hormonal and radiologic studies including rapid ACTH stimuation test and furosemide challenge test.(Korean J Med 69:S846-S850, 2005) |
| Key Words:
Adrenal gland hypofunction, Metastasis, Bronchogenic carcinoma |
|
PDF Links
Full text via DOI
Download Citation
