Korean J Med > Volume 88(2); 2015 > Article
The Korean Journal of Medicine 2015;88(2):212-217.
Published online February 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.88.2.212   
A Case of Acute Pancreatitis: Portal Vein Superimposed Thrombosis in a Nephritic Syndrome Patient
Nak Min Kim, Ji Hyung Yoo, Woo Kyung Sung, Su A Yun, Jin Uk Jeong, Jong Ho Shin, Ki Tae Bang
Department of Internal Medicine, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea
신증후군 환자에서 병발한 간문맥 혈전증 및 급성 췌장염 1예
김낙민, 유지형, 성우경, 윤수아, 정진욱, 신종호, 방기태
을지대학교 의과대학 을지대학교병원 내과
Correspondence: 
Ki Tae Bang, Tel: +82-42-611-300, Fax: +82-42-259-1162, Email: starryroom@eulji.ac.kr
Received: 3 April 2014   • Revised: 3 June 2014   • Accepted: 30 July 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Nephrotic syndrome is characterized by hypercoagulability and thrombosis of the renal and deep veins. We describe a case of unusual thrombosis in the portal and superior mesenteric veins of a 41-year-old female, admitted for treatment of abdominal pain, who simultaneously presented with nephrotic syndrome and acute pancreatitis. Laboratory analysis revealed hypoalbuminemia, hyperlipidemia, and proteinuria. Abdominal computed tomography revealed acute pancreatitis, thrombosis at the portal and superior mesenteric veins, and ischemic changes in the colon and small intestines. Anticoagulation therapy was started immediately. Abdominal pain was subsequently reduced and the ischemic lesion disappeared. Warfarin use could not be terminated immediately. Empirical steroid therapy commenced without a kidney biopsy. Complete remission occurred after 4 weeks. Following warfarin cessation, a kidney biopsy was performed, confirming the diagnosis of minimal change disease.
Key Words: Nephrotic syndrome; Pancreatitis
주제어: 신증후군; 췌장염


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