Korean J Med > Volume 77(5); 2009 > Article
The Korean Journal of Medicine 2009;77(5):1183-1187.
A case of organizing pneumonia with cryoglobulinemia
Yeon Jae Kim, Sang Heon Kim, Tae Hyung Kim, Ho Joo Yun, .Dong Ho Shin, Sung Soo Park, Jang Won Sohn
한랭글로불린혈증에서 동반된 기질화 폐렴 1예
김연재·김상헌·김태형·윤호주·신동호·박성수·손장원, Sang Heon Kim, Tae Hyung Kim, Ho Joo Yun, .Dong Ho Shin, Sung Soo Park, Jang Won Sohn
Abstract
Cryoglobulinemia refers to the presence of serum polyclonal immunoglobulins that precipitate reversibly at cold temperature. Cryoglobulinemia can involve various organs, including the skin, liver, kidney, and lung. Although many diseases can lead to organizing pneumonia, reports of organizing pneumonia with cryoglobulinemia (OPC) are rare. We treated a case of prolonged migrating patchy lung infiltration combined with mixed cryoglobulinemia. A 75-year-old man was admitted with progressive dyspnea and cough. The serological, clinical, and pathological findings confirmed the presence of mixed cryoglobulinemia. A chest radiograph and computed tomography (CT) showed multiple patchy consolidations that did not resolve with empirical antibiotic treatment. Additionally, his symptoms did not respond to antibiotics. The transbronchial lung biopsy showed organizing pneumonia, so steroid treatment was started, and the clinical symptoms and radiological findings improved. (Korean J Med 77:S1183- S1187, 2009)
Key Words: Organizing pneumonia; Cryoglobulinemia


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