Korean J Med > Volume 76(2); 2009 > Article
The Korean Journal of Medicine 2009;76(2):209-214.
A case of CMV-induced gastric ulcer
Mi-Jeong Lee, Jae Myung Park, Yoo Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, In-Sik Chung
거대세포바이러스에 의해 유발된 위궤양
이미정 &#; 박재명 &#; 조유경 &#; 이인석 &#; 김상우 &#; 최명규 &#; 정인, Jae Myung Park, Yoo Kyung Cho, In Seok Lee, Sang Woo Kim, Myung-Gyu Choi, In-Sik Chung
Abstract
A 59-year-old female with breast cancer, who had been treated with cancer chemotherapy and radiotherapy, visited the hospital with a 2-week history of epigastric pain. Upper gastrointestinal endoscopy showed multiple ulcers with gastric hypertrophy. In the biopsy specimen, no malignant cells were observed, but some cells were positive on immunochemistry examination for cytomegalovirus (CMV). Ganciclovir was administered for 2 weeks. Her symptoms improved and the immunochemistry finding of a subsequent gastric mucosal specimen was negative. However, the lumen of the gastric antrum was too narrow for the endoscope to pass the pylorus easily. A gastric perforation resulted and was treated with total gastrectomy and esophagojejunostomy, while an endoscopic stent was inserted to allow oral intake. Here, we report a case of gastric ulcer resulting from CMV infection and stenosis as a complication in an immunosuppressant patient. (Korean J Med 76:209-214, 2009)
Key Words: Cytomegalovirus; Gastric ulcer; Immunosuppression; Stricture


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