A case of ulcerative colitis combined with primary sclerosing cholangitis, diagnosed by MR cholangiography

Ji Won Ryou,; Young Sook Park,; Seong Hwan Kim,; Mun Hee Song,; Han Hyo Lee,; Sang Yoon Shin,; Jun Seok Lee,

Korean J Med > Volume 73(3); 2007 > Article

Original Article

The Korean Journal of Medicine 2007;73(3):890-894.

A case of ulcerative colitis combined with primary sclerosing cholangitis, diagnosed by MR cholangiography

Ji Won Ryou, Young Sook Park, Seong Hwan Kim, Mun Hee Song, Han Hyo Lee, Sang Yoon Shin, Jun Seok Lee

경희대학교 의과대학 순환기내과학교실

증례 : 궤양성 대장염 환자에서 MRCP로 진단한 원발성 경화성 담관염 1예

류지원&#;박영숙&#;김성환&#;송문희&#;이한효&#;신상윤&#;이준석, Young Sook Park, Seong Hwan Kim, Mun Hee Song, Han Hyo Lee, Sang Yoon Shin, Jun Seok Lee

Abstract

Ulcerative colitis (UC) is frequently associated with many extraintestinal manifestations. Among them, primary sclerosing cholangitis (PSC) shows a 1～5% incidence in patients with UC. PSC is a progressive inflammatory disease affecting the extrahepatic and intrahepatic bile ducts, characteristic radiologic and histologic findings. PSC is not correlated with the course of UC. We report a 25-year-old man with UC combined with PSC. He was diagnosed with UC 6 years ago. Four years ago, ERCP was done due to his abnormal liver function test (LFT), but it showed no abnormal findings. At this time, he again presented with fatigue and an abnormal LFT. For investigating the extrahepatic and intrahepatic bile ducts, we checked the MRCP. His MRCP showed mild dilatation of the peripheral portion of both intrahepatic ducts with multiple strictures, which was compatible with PSC. We prescribed UDCA for him and he was followed regullary.(Korean J Med 73:S890-S894, 2007)

Key Words: Ulcerative colitis, Primary sclerosing cholangitis, Cholangiography, Magneti cresonance