Korean J Med > Volume 77(5); 2009 > Article
The Korean Journal of Medicine 2009;77(5):1337-1341.
Microscopic polyangiitis presenting with painless anal bleeding
Seung Woo Han, Hyuck Yong Kwon, Jong Kyu Kwon, Jin Woo Choi, Kyung Sook Lee, Kyung Rak Sohn, Gun Woo Kim
무통성 항문출혈로 발현한 현미경적 다발혈관염 1예
한승우·권혁용·권종규·최진우·이경숙·손경락·김건우, Hyuck Yong Kwon, Jong Kyu Kwon, Jin Woo Choi, Kyung Sook Lee, Kyung Rak Sohn, Gun Woo Kim
Abstract
Microscopic polyangiitis (MPA) is a systemic vasculitis that is characterized by small-vessel involvement histologically. Although MPA is primarily associated with necrotizing and crescentic glomerulonephritis and pulmonary capillaritis, it often has gastrointestinal (GI) involvement. The most frequent GI symptom in MPA is abdominal pain of an ischemic nature, while GI bleeding is rare. We report a case of MPA that presented with painless anal bleeding, which was initially misdiagnosed as an internal hemorrhoid. The surgical specimen of the anus showed vasculitis of small arteries with fibrinoid necrosis and the renal biopsy showed necrotizing glomerulonephritis with tubular atrophy. To our knowledge, this is the first reported case of anal involvement in MPA. (Korean J Med 77:S1337-S1341, 2009)
Key Words: Microscopic polyangiitis; Gastrointestinal involvement; Glomerulonephritis


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