Korean J Med > Volume 74(1); 2008 > Article
The Korean Journal of Medicine 2008;74(1):37-41.
Portal and splenic vein thrombosis successfully treated with low molecular weight heparin in acute pancreatitis
Ji Young Cheun, Tae Hee Lee, Yong Suk Kim, Dae Seung Lim, Sun Moon Kim, Euyi Hyeog Im, Kyu Chan Huh
경희대학교 의과대학 순환기내과학교실
증례 : 저분자량 헤파린 치료한 급성 췌장염에서의 간문맥과 비장정맥 혈전증
천지영, 이태희, 김용석, 임대승, 김선문, 임의혁, 허규찬
Abstract
Combined portal and splenic vein thrombosis is an uncommon disease entity, which may result from inherited prothrombotic disorders, malignancy, and inflammatory states like pancreatitis. The natural history of portal vein thrombosis is unknown. Spontaneous repermeation is uncommon, whereas repermeation can be achieved with anticoagulant therapy in more than 80% of cases. Repermeation prevents ischemic intestinal injury and extrahepatic portal hypertension. However, the standard protocol for anticoagulation in portal vein thrombosis has not yet been determined. We present a 67-year-old man who had portal and splenic vein thrombosis in the setting of acute pancreatitis, which was successfully treated with low molecular weight heparin.
Key Words: Pancreatitis; Portal and splenic vein thrombosis; Low molecular weight heparin


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