| Home | E-Submission | Sitemap | Contact Us |  
Korean J Med > Volume 88(4); 2015 > Article
The Korean Journal of Medicine 2015;88(4): 424-429.
크론병 환자에서 발생한 간세포암 1예
장승현, 김지현, 이재우, 이준영, 조영윤, 최원묵, 정현채
서울대학교 의과대학 내과학교실, 간연구소
A Case of Hepatocellular Carcinoma in a Patient with Crohn’s Disease
Seung Hyeon Jang, Jee Hyun Kim, Jae Woo Lee, June Young Lee, Young Youn Cho, Won-Mook Choi, Hyun Chae Jung
Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Hyun Chae Jung ,Tel: +82-2-740-8112, Fax: +82-2-743-6701, Email: hyunchae@snu.ac.kr
Received: May 1, 2014;   Revised: September 1, 2014;   Accepted: October 25, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Hepatocellular carcinomas (HCCs) in patients with Crohn’s disease (CD) without underlying chronic hepatitis or liver cirrhosis are extremely rare. Previously reported cases occurred in patients who had developed CD at a young age and had been treated with immunosuppressive agents long-term. We herein report the first case of HCC in a 34-year-old patient with CD in Korea. The patient was treated with azathioprine for 14 years and had undergone repeated surgeries for CD. During the follow-up period, the patient was hospitalized for colon perforation and pericolic abscess formation. Computed tomography showed a liver mass, and HCC was diagnosed based on liver biopsy. The patient underwent right hemicolectomy for colon perforation and transcatheter arterial chemoembolization followed by radiofrequency ablation for the HCC. The present case is similar to previously reported cases with the exception of the liver pathology findings, which exhibited neither primary sclerosing cholangitis nor focal hepatic glycogenolysis.
Keywords: Hepatocellular carcinoma; Crohn disease; Azathioprine; Infliximab
Editorial Office
101-2501, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-2271-6791   Fax: +82-2-790-0993    E-mail: kaim@kams.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © The Korean Association of Internal Medicine. All rights reserved.                powerd by m2community