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Korean J Med > Volume 88(2); 2015 > Article
The Korean Journal of Medicine 2015;88(2): 127-134.
좌심실 수축 기능 저하 심부전증의 치료
박진주1,2, 최동주1,2,3
1서울대학교 의과대학 분당서울대학교병원 심장혈관센터
2서울대학교 의과대학 분당서울대학교병원 내과
3서울대학교 의과대학 내과학교실
Treatment of Heart Failure with Reduced Ejection Fraction: Current Update
Jin Joo Park1,2, Dong-Ju Choi1,2,3
1Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Korea
2Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
3Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Dong-Ju Choi ,Tel: +82-31-787-7007, Fax: +82-31-787-4290, Email: djchoi@snu.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
The prevalence of heart failure (HF) has been steadily increasing and it now creates an enormous social and economic burden. HF is a syndrome characterized by a high mortality rate, frequent hospitalization, a reduced quality of life, and a complex therapeutic regimen. In the last three decades, major progress in both the diagnosis and management of HF has taken place, and the pharmacologic and non-pharmacologic advances have led to a significant improvement in survival and symptoms in HF patients. After an accurate diagnosis, a proper HF management plan requires a multi-level team approach comprised of the correct combination of drug therapy, device therapy, and surgery, including heart transplantation. In this review, we focused on the pharmacologic and non-pharmacologic treatment strategies for HF with reduced ejection fraction. The goal was to develop treatment guidelines based on significant evidence derived from large clinical trials.
Keywords: Systolic heart failure; Practice guideline
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