Korean J Med > Volume 78(6); 2010 > Article
The Korean Journal of Medicine 2010;78(6):766-770.
A case of peripheral T-cell lymphoma presenting with a necrotizing gingival ulcer
Hong-Sung Chough, Yu-Jin Jeong, Jung-Yeon Han, Hyun-Sook Kim
건양대학교 의과대학 1내과학교실, 2방사선종양학과
괴사성 잇몸궤양으로 나타난 말초 T세포 림프종 1예
조홍성, 정유진, 한정연, 김현숙
Departments of 1Internal Medicine and 2Radiation Oncology, Konyang University College of Medicine, Daejeon, Korea
Abstract
Peripheral T-cell lymphoma (PTCL) is a heterogenous group of generally aggressive neoplasms constituting less than 15% of all non-Hodgkin’s lymphomas in adults. PTCL unspecified (PTCL-U) comprises 6% of lymphomas in the United States and Europe. Most patients with PTCL-U present with generalized lymphadenopathy and hemophagocytosis, eosinophilia, and pruritus involving the skin, liver, spleen, and other viscera. Gingival and genital ulcers are a very uncommon manifestation. The diagnosis of PTCL-U is based on the results of a tissue biopsy that shows evidence of T-cell lymphoma that does not meet the criteria for other subtypes of T-cell lymphoma. Here, we describe an 85-year-old man with intermittent fever and necrotizing gingival and genital ulcers who was diagnosed with PTCL-U after a gingival biopsy. (Korean J Med 78:766-770, 2010)
Key Words: Peripheral T-cell lymphoma; Gingival ulcer


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