| A case of therapeutic LDL apheresis in familial hypercholesterolemia |
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Bu Ghil Lee, Kyoung Hoon Lee, Jang-Young Kim, Ohgun Kwon, Young Uh |
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전남대학교병원 심장센터, 간호부, 전남대학교 심혈관계 특성화 사업단 |
| 증례 : 가족성 고콜레스테롤 환자에서의 LDL apheresis 치료 1예 |
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이부길, 이경훈, 김장영, 권오건, 어 영 |
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| Abstract |
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Familial hypercholesterolemia (FH) is an autosomal dominant metabolic disorder caused by a mutation in the low density lipoprotein receptor (LDLR) gene. Hypercholesterolemia is usually successfully treated with a statin. However, such medications often have insufficient cholesterol-lowering effect or are not well-tolerated. In these cases, LDL apheresis is an option. LDL apheresis provides an effective alternative for treating patients with FH and preventing the progression of coronary artery disease (CAD). Although there are many reports on LDL apheresis, none has been related to cases in Korea. We report the case of a 20-year-old male patient who was admitted for chest pain and diagnosed with severe CAD and familial hypercholesterolemia. LDL cholesterol was controlled with lipid-lowering agents and LDL apheresis. |
| Key Words:
Familial hypercholesterolemia; LDL apheresis |
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