Korean J Med > Volume 74(3); 2008 > Article
The Korean Journal of Medicine 2008;74(3):330-335.
Effect of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: Report of 3 cases
Eun-Kee Song, Na-Ri Lee, Jae-Yong Kwak, Chang-Yeol Yim
성균관 의과대학교 삼성서울병원 심혈관센터 순환기내과
증례 : 특발성혈소판감소증에서 위나선균 제균요법의 효과 : 세 가지 증례 보고
송은기 . 이나리 . 곽재용 . 임창열, Na-Ri Lee, Jae-Yong Kwak, Chang-Yeol Yim
Abstract
There are several reports suggesting Helicobacter pylori can initiate and perpetuate idiopathic thrombocytopenic purpura (ITP) and eradication of H. pylori can increase the platelet counts, however, the prevalence of H. pylori infection in patients with ITP is similar to that found in the general population and a recovery of thrombocytopenia after H. pylori eradication therapy has not been identified reliably. We report three different cases of H. pylori infected patients with ITP who recovered completely after eradication of H. pylori. The first case was refractory, the second was recurred after conventional treatment for ITP, and the third was treated with H. pylori eradication on first line treatment. We believe that the eradication of H. pylori is useful in some patients with ITP in Korea and well controlled randomized study is necessary for further identification of such population. (Korean J Med 74:330-335, 2008)
Key Words: Helicobacter pylori; Idiopathic thrombocytopenic purpura


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