| The clinical characteristics of elderly onset rheumatoid arthritis |
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Jung Hyun Park, Gyu Lee, Jin Woo Go, Sung Nam Park, Wha Jung Lee, Gwang Sun Ahn, Choong Won Lee |
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고려대학교 의과대학 내과학교실 |
| 원저: 노인성 류마티스 관절염의 임상적 특징 |
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박정현, Gyu Lee, Jin Woo Go, Sung Nam Park, Wha Jung Lee, Gwang Sun Ahn, Choong Won Lee |
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| Abstract |
Background : Elderly-onset rheumatoid arthritis (EORA) is considered to be different from younger-onset rheumatoid arthritis (YORA) in clinical manifestations, laboratory indices, and in
prognosis. However, the differences between these two diseases have not been clearly defined. The aim of this study was to more clearly define the clinical characteristics of EORA.
Methods
: We retrospectively reviewed 50 EORA and 58 YORA patients who met the classification criteria established by the American College of Rheumatology (ACR). The two groups
(EORA and YORA) were compared by three criteria. First, we considered the patterns of the joints involved and the presence of rheumatoid nodules. Second, we compared the disease activity indices and the level of auto-antibodies. Finally, we compared the use of medications.
Results
: The mean age-of-onset and the women-to-men ratio in the EORA group was 66.2¡¾5.5 years and 2.1:1, respectively. There was more large joint involvement seen in the EORA group. The
titer of disease activity indices (ESR, CRP) and positive rate of auto-antibodies (rheumatoid factor, ANA, but not anti-CCP antibody) were also higher in the EORA group. We found no differences in
the prescribed medications between the two groups.
Conclusions
: From these studies, we believe that EORA has higher disease activity indices at onset and greater joint involvement, along with higher titers of auto-antibodies as compared to YORA.(Korean J Med 72:62-67, 2007)
Key Words : Rheumatoid arthritis, Aging |
| Key Words:
Rheumatoid arthritis, Aging |
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