Korean J Med > Volume 71(6); 2006 > Article
The Korean Journal of Medicine 2006;71(6):694-698.
A case of primary esophageal T-cell malignant lymphoma
Yang Chun Han, Myoung Joo Kang, Jeong Ha Park, Won Sik Lee, Chang Hak Sohn, Chan Hwan Kim, Young Don Joo
고려대학교 의과대학 내과학교실
원발성 식도 T 세포 악성림프종 1예
한양천, Myoung Joo Kang, Jeong Ha Park, Won Sik Lee, Chang Hak Sohn, Chan Hwan Kim, Young Don Joo
Abstract
Gastrointestinal tract (GIT) lymphomas usually originate from B-lymphocytes but rarely from T-lymphocytes. The stomach is the most common site for extranodal GIT lymphoma but the esophagus is a rare site. In addition, a primary esophageal T-cell lymphoma is an uncommon disorder. We encountered a case of a primary esophageal T-cell lymphoma in a 60-year-old man, who had swallowing difficulties and multiple ulcers in the upper and lower esophageal mucosa on gastroscopy. Immunohistochemical staining for the biopsy material from the multiple esophageal ulcers tested positive for LCA and CD45RO (pan T-cell marker) and negative for cytokeratin and CD20 reactivity, respectively. No other abnormal lesions were observed on a computed tomography scan of the neck, chest, abdomen and pelvis. After six cycles of combination chemotherapy with cyclophosphamide, adriamycin, vincristin, prednisolone, etoposide and gemcitabine, the multiple esophageal ulcers had completely disappeared suggesting a complete clinical response. We report this case with a review of the relevant literature(Korean J Med 71:694-698, 2006) Key Words : Esophagus, T-cell lymphoma


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