Korean J Med > Volume 86(3); 2014 > Article
The Korean Journal of Medicine 2014;86(3):282-294.
Published online March 1, 2014.
DOI: https://doi.org/10.3904/kjm.2014.86.3.282   
Diagnosis and Management of Central Venous Catheter-Related Infections
Ki-Ho Park
Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea
중심정맥관 관련 감염의 진단과 치료
박기호
경희대학교 의과대학 내과학교실
Correspondence: 
Ki-Ho Park, Tel: +82-2-958-2966, Fax: +82-2-968-1848, Email: parkkiho@hotmail.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Use of central venous catheters (CVCs) can lead to catheter-related bloodstream infections (CRBSIs) and such infections are associated with serious morbidity and mortality and with increased health care costs. The diagnosis of CRBSI needs to be accurate for adequate management. Semiquantitative catheter tip culture has been established as standard in most laboratories, but this method requires catheter removal. Catheter-sparing diagnostic methods, such as differential quantitative blood cultures and differential time to positivity have emerged as reliable diagnostic techniques. Management of CRBSIs involves deciding on catheter removal and the type and duration of systemic antimicrobial therapy. Such decisions depend on the identity of the organism causing the bloodstream infection and the clinical and radiographic manifestations suggesting a complicated course. (Korean J Med 2014;86:282-294)
Key Words: Central venous catheter; Bloodstream infection; Bacteremia; Diagnosis; Treatment
주제어: 중심정맥관; 혈류감염; 균혈증; 진단; 치료


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