| A 55-Year-Old Man Presenting with Recurrent Upper Abdominal Pain |
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Jun Tae Park1, Hyung Ku Chon2, Keum Ha Choi3 |
1Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine, Iksan, Korea
2Division of Biliopancreas, Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine, Iksan, Korea
3Department of Pathology , Wonkwang University Hospital, Wonkwang University School of Medicine, Iksan, Korea |
| 반복적인 상복부 통증으로 내원한 55세 남자 |
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박준태1, 전형구2, 최금하3 |
1원광대학교 의과대학 원광대학교병원 내과
2원광대학교 의과대학 원광대학교병원 췌장담도내과
3원광대학교 의과대학 원광대학교병원 병리과 |
Correspondence:
Hyung Ku Chon, Tel: +82-63-859-1676, Fax: +82-63-855-2025, Email: gipb2592@wku.ac.kr
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Received: 28 February 2025 • Revised: 20 March 2025 • Accepted: 25 March 2025 |
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| Abstract |
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IgG4-related autoimmune pancreatitis (IgG4-AIP) is an immune-mediated disease that can present as recurrent acute pancreatitis with biliary involvement. We report a case of a 55-year-old male with recurrent acute pancreatitis and obstructive jaundice of unknown cause. Laboratory tests revealed elevated IgG and IgG4 levels, while imaging showed pancreatic swelling, main pancreatic duct stricture, and distal bile duct stenosis. Endoscopic ultrasound-guided biopsy confirmed IgG4-positive plasma cell infiltration and fibrosis, leading to a diagnosis of IgG4-AIP. The patient responded well to corticosteroid therapy, with clinical and radiologic improvement, and was placed on low-dose maintenance therapy to prevent recurrence. IgG4-AIP should be considered in patients with idiopathic recurrent pancreatitis, and early recognition is crucial to avoid unnecessary interventions. Corticosteroids remain the mainstay of treatment, but long-term monitoring is essential due to the risk of recurrence and potential complications. |
| Key Words:
Pancreatitis; Autoimmune Pancreatitis; Steroid |
| 주제어:
췌장염; 자가면역성 췌장염; 스테로이드 |
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