| A case of essential thrombocythemia with hashitoxicosis and Hürthle cell adenoma |
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Seul Ki Min, Seung Jin Kong, Ho Gwon Lee, Dong Hun Shin, Hun Ho Song, Seong Jin Lee, Moon Gi Choi |
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Department of Medicine, Sungkyunkwan University School of Medicine |
| 증례 : 하시모토 갑상선중독증 및 휘트르레 선종과 동반된 본태성 혈소판증가증 1예 |
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민슬기&#;공승진&#;이호권&#;신동훈&#;송헌호&#;이성진&#;최문기, Seung Jin Kong, Ho Gwon Lee, Dong Hun Shin, Hun Ho Song, Seong Jin Lee, Moon Gi Choi |
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| Abstract |
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Hashitoxicosis, a rare cause of primary hyperthyroidism, is diagnosed by presence of thyrotropin receptor antibody, increased radioiodine uptake and histological finding of lymphoid follicle with lymphcytic infiltration. Thrombocytopenia associated with hyperthyroidism including hashitoxicosis is probably caused by increased destruction of platelets in reticuloendothelial phagocytic system although it is partially compensated by increased production of magakaryocytes in bone marrow.
Because essential thrombocythemia in hyperthyroid state has not been reported, most cases of thrombocytosis developed in the treatment of hyperthyroidism are considered as secondary thrombocytosis without any further examination. We experienced fourty-seven year-old woman presenting with palpitation and anterior neck swelling. By endocrinological and histological examinations, she was diagnosed as hashitoxicosis and Hürthle cell adenoma. For evaluation of progressive thrombocytosis, bone marrow biopsy was performed, in which essential thrombocythemia was diagnosed. In summary, we report the first case of an essential thrombocythemia with hashitoxicosis and Hürthle cell adenoma.(Korean J Med 69:S856-S860, 2005) |
| Key Words:
Thyrotoxicosis, Hürthle cell tumor, Thrombocytosis |
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