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Korean J Med > Volume 94(6); 2019 > Article
The Korean Journal of Medicine 2019;94(6): 495-499.
패혈증
이용희, 조영재
분당서울대학교병원 호흡기내과
Sepsis
Yunghee Lee, Young-Jae Cho
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
Corresponding Author: Young-Jae Cho ,Tel: +82-31-787-7058, Fax: +82-31-787-4050, Email: lungdrcho@snubh.org
Received: October 10, 2019;   Revised: October 21, 2019;   Accepted: October 21, 2019.
ABSTRACT
Diagnosis and treatment criteria were recently updated based on the Sepsis-3 guidelines, which recommend the sequential organ failure assessment for accurate characterization of organ dysfunction. Large randomized controlled trials have found neutral results with early goal-directed therapy. To improve outcomes, treatment bundles incorporating standards for early sepsis treatment, including antibiotic and steroid treatment, were developed. Thus, future research should address the effects of steroids and immune-modulating agents on refractory septic shock as well as the development of new coagulopathy therapies and dynamic assessment tools.
Keywords: Sepsis; Shock, Septic; Systemic inflammatory response syndrome
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