Korean J Med > Volume 89(1); 2015 > Article
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The Korean Journal of Medicine 2015;89(1):21-26.
Published online July 1, 2015.
DOI: https://doi.org/10.3904/kjm.2015.89.1.21   
Medical Management of Obstructive Sleep Apnea
Jinsoo Min1, Se Joong Kim2
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea
2Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea
폐쇄성 수면 무호흡증의 내과적 치료
민진수1, 김세중2
1충북대학교 의과대학 충북대학교병원 호흡기내과
2서울대학교 의과대학 분당서울대학교병원 호흡기내과
Correspondence: 
Se Joong Kim, Tel: +82-31-787-7076, Fax: +82-31-787-4052, Email: ksj1146@snubh.org
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Obstructive sleep apnea (OSA) is a prevalent disorder characterized by repeated episodes of obstructive apnea and hypopnea due to repetitive collapse of the upper airway during sleep. OSA should be suspected in patients that are obese, hypertensive, habitual snorers, and hypersomnolent. Standard overnight polysomnography is essential for proper diagnosis. OSA is a chronic disease that requires long-term multidisciplinary care. Management of this condition begins with patient education. Behavior modifications, such as weight loss, exercising, changing the sleep position, abstaining from alcohol, and avoiding certain medications, are essential for most patients with OSA. Positive airway pressure (PAP) is the mainstay therapy for OSA, and its initiation requires selection of an appropriate device and mode of PAP. The optimal pressure is determined by titration during the second polysomnography. Continuous positive airway pressure (CPAP) is the first-line therapy for moderate to severe OSA. Due to low compliance rates of CPAP, it is important to educate patients and manage complications associated with mask and pressure-related discomfort as early as possible. Bi-level PAP or auto-titrating PAP is an acceptable options for patients that cannot tolerate CPAP. In cases of mild to moderate OSA, an oral appliance can be used as a reasonable alternative therapy.
Key Words: Sleep apnea, Obstructive; Diagnosis; Treatment; Continuous positive airway pressure
주제어: 폐쇄성 수면 무호흡증; 진단; 치료; 지속형 양압기


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