| Pyogenic Liver Abscess: Changes in Clinical Features over the Last 10 Years |
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Joo Ho Park, Tae Hee Lee, Min Gyu Kang, Mi Young Lee, Myung Jun Lee, Jin Sil Pyo, Jung Ho Park, Hoon Sup Koo, Kyung Ho Song, Yong Seok Kim, Sun Moon Kim, Kyu Chan Huh, Young Woo Choi, Young Woo Kang |
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Department of Internal Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea |
| 화농성 간농양; 최근 10년간의 임상적 특징의 변화 양상 |
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박주호, 이태희, 강민규, 이미영, 이명준, 표진실, 박정호, 구훈섭, 송경호, 김용석, 김선문, 허규찬, 최용우, 강영우 |
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건양대학교 의과대학 건양대학교병원 내과 |
Correspondence:
Tae Hee Lee, Tel: +82-42-600-9370, Fax: +82-42-600-9090, Email: green740@naver.com
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Received: 27 December 2014 • Revised: 23 January 2015 • Accepted: 26 February 2015 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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| Abstract |
Background/Aims
A pyogenic liver abscess is an acute bacterial infection that can potentially lead to life-threatening sepsis. This study examined the clinical features and changing trends of pyogenic liver abscess over the last 10 years.
Methods
We investigated patient characteristics, laboratory findings, blood and abscess culture results, location and characteristics of the abscess, and treatment modality in the medical records of 146 patients. We divided them into three groups by period: period 1, 23 patients in 2002-2003; period 2, 46 patients in 2007-2008; and period 3, 77 patients in 2012-2013.
Results
The mean patient age was 64.3 ± 15.1 years and 87 of the 146 patients were male (59.6%). Period 2 had a higher prevalence of chronic alcoholics (30.4% vs. 10.4%) and lower prevalence of fever and chills (73.9% vs. 92.2%) compared with period 3. Klebsiella pneumoniae was the most commonly cultured bacteria and the microbiological findings did not differ among the three periods. Pyogenic liver abscesses were more common in the right liver. The lengths of hospital stay and treatment modalities were similar in all three periods.
Conclusions
Although there were slight differences in symptoms among the periods, there were no changes in the liver abscess characteristics, i.e., location, size, and culture results. As there were no changes, the treatment strategy also did not change. We should continue to investigate the clinical features of liver abscess. |
| Key Words:
Liver abscess; Klebsiella pneumoniae; Drainage |
| 주제어:
간농양; Klebsiella pneumoniae; 배농 |
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