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Korean J Med > Volume 88(5); 2015 > Article
The Korean Journal of Medicine 2015;88(5): 487-501.
다제내성 그람양성균 감염증
정영희1,2,3, 김홍빈1,2
1서울대학교 의과대학 내과학교실
2분당서울대학교병원 감염내과
3건양대학교 의과대학 건양대학교병원 내과
Multidrug-Resistant Gram-Positive Bacterial Infections
Younghee Jung1,2,3, Hong Bin Kim1,2
1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
2Division of Infectious Diseases, Seoul National University Bundang Hospital, Seongnam, Korea
3Department of Internal Medicine, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea
Corresponding Author: Hong Bin Kim ,Tel: +82-31-787-7021, Fax: +82-31-787-4052, Email: hbkimmd@snu.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Antimicrobial resistance threatens the effective treatment of bacterial infections and is a serious problem worldwide. Multidrug-resistant bacteria are difficult to treat and the treatment outcome is worse than with susceptible bacteria. In Korea, the antibiotic resistance rates of the major Gram-positive bacteria methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), and penicillin-resistant Streptococcus pneumoniae (PRSP) are very high. Clinicians should know the risk factors for developing multidrug-resistant bacterial infection, update the changing local epidemiology of resistant bacteria, and choose appropriate antibiotics in clinical practice. The overuse and misuse of broad spectrum antibiotics should be avoided. This review focuses on the epidemiology and risk factors of MRSA, VRE, and PRSP, the major multidrug-resistant Gram-positive bacteria.
Keywords: Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant enterococcus; Penicillin-resistant Streptococcus pneumoniae
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