| Case of Sarcoidosis-Related Hypercalcemia with Normal Serum 1,25(OH)2D |
|
Jae-Han Jeon1, Jung-Bum Seo1, In-Ryang Hwang1, Hye-Yoon Park1, Jeong-Shik Kim2, Keun-Gyu Park1, Jung-Guk Kim1 |
1Departments of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
2Departments of Pathology, Kyungpook National University School of Medicine, Daegu, Korea |
| 고칼슘혈증 동반 사르코이드증에서 정상 혈중 비타민 D를 보인 증례 |
|
전재한1, 서정범1, 황인량1, 박혜윤1, 김정식2, 박근규1, 김정국1 |
1경북대학교 의학전문대학원 내과학교실
2경북대학교 의학전문대학원 병리과학교실 |
Correspondence:
Jung-Guk Kim, Tel: +82-53-200-5566, Fax: +82-53-426-6722, Email: jugkim@knu.ac.kr
|
|
Received: 22 November 2013 • Revised: 7 January 2014 • Accepted: 11 July 2014 |
|
|
| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Abstract |
|
Diagnosing hypercalcemia is often challenging because a wide spectrum of diseases-such as malignancy, granulomatous disease, and primary hyperparathyroidism-should be considered. Sarcoidosis is a rare cause of hypercalcemia. The case of a 77-year-old male presenting with sarcoidosis-associated hypercalcemia whose serum 1,25(OH)2D level was normal is reported here. Despite a normal 1,25(OH)2D level and minimally enlarged hilar lymphadenopathy, the serum angiotensin-converting enzyme (ACE) level was increased. Mediastinoscopic biopsy of the right lower paratracheal lymph node revealed pathological findings compatible with sarcoidosis. Treatment with 30 mg/day oral prednisone was started. Currently, the patient is being treated with a tapered dose of oral prednisone and small doses of vitamin D and calcium. Despite its low incidence, sarcoidosis should be considered a cause of hypercalcemia. The important diagnostic factors are not only serum calcitriol levels but also serum ACE levels and pathological findings. |
| Key Words:
Hypercalcemia; Sarcoidosis; Vitamin D |
| 주제어:
고칼슘혈증; 사르코이드증; 비타민 D |
|
PDF Links
Full text via DOI
Download Citation
