Dyslipidemia Treatment in Diabetes Mellitus Patients |
Sung Rae Kijm |
Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea |
당뇨병 환자에서 이상지질혈증의 치료 |
김성래 |
가톨릭대학교 의과대학 내분비대사내과 |
Correspondence:
Sung Rae Kijm, Tel: +82-32-340-7013, Fax: +82-32-340-2039, Email: kimsungrae@catholic.ac.kr |
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Abstract |
Cardiovascular disease (CVD) is the major cause of mortality and morbidity in patients with type 2 diabetes mellitus. The increased risk of CVD in subjects with type 2 diabetes mellitus involves multiple factors, including hypertension, smoking, albuminuria, and hypercholesterolemia. Of these, hypercholesterolemia is amenable to intervention. A large body of research ranging from molecular to population studies indicates that elevated low-density-lipoprotein cholesterol (LDL-C) is a major predictor of CVD, including in the population with diabetes. Despite available therapies and increased attention to hypercholesterolemia, many patients fail to achieve the LDL-C goals. A patient-tailored approach to dyslipidemia therapy, as determined by baseline LDL-C levels, is an effective strategy for achieving target LDL-C levels. |
Key Words:
Type 2 diabetes mellitus; Cardiovascular disease; Hypercholesterolemia; LDL cholesterol |
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