| Case of Successful Radiofrequency Ablation of Multiple Bilateral Renal Cell Carcinomas in von Hippel-Lindau Disease |
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Sang Yi Moon, Dong Hyun Kim, Eui Han Jung, So Young Park, Mi Kyung Park, Duk Kyu Kim, Sunghwan Suh |
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Departments of Internal Medicine, College of Medicine, Dong-A University, Busan, Korea |
| 다발·양측성 신세포암이 발병한 폰히펠린다우병 환자의 고주파 절제술 |
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문상이, 김동현, 정의한, 박소영, 박미경, 김덕규, 서성환 |
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동아대학교 의과대학 내과학교실 |
Correspondence:
Sunghwan Suh, Tel: +82-51-240-2747, Fax: +82-51-240-5852, Email: suhs@dau.ac.kr
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Received: 19 October 2013 • Revised: 19 February 2014 • Accepted: 11 March 2014 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Abstract |
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Von Hippel-Lindau (VHL) disease is an inherited, autosomal dominant syndrome that manifests as a variety of benign and malignant tumors in various organs. Notably, renal cell carcinoma (RCC) in patients with VHL disease tends to be multifocal and bilateral, and tends to recur or new tumors develop after removal. Radiofrequency ablation (RFA) has recently been introduced as a minimally invasive treatment for small hereditary RCCs with a low complication rate and a minimal decrease in renal function. We present a case of successful RFA of multiple bilateral RCCs in a 24-year-old female with VHL. Computed tomography (CT) of the abdomen revealed multiple bilateral RCCs. The patient received sequential RFA for the bilateral RCCs, resulting in a complete response. At the time of writing, there was no sign of recurrence or renal failure. In conclusion, percutaneous RFA is a promising treatment for VHL patients who cannot undergo surgery, with excellent treatment outcomes and minimal change in renal function. |
| Key Words:
von Hippel Lindau Disease; Renal cell carcinoma; Ablation |
| 주제어:
폰히펠-린다우병; 신세포암; 카테터 절제술 |
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