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Korean J Med > Volume 87(4); 2014 > Article
The Korean Journal of Medicine 2014;87(4): 401-414.
혈관염의 새로운 분류기준
김혜원, 허진욱
을지대학교 의과대학 을지병원 류마티스 내과
Update on the Classification Criteria for Vasculitis
Hye Won Kim, Jin-Wuk Hur
Division of Rheumatology, Department of Internal Medicine, Eulji University College of Medicine, Eulji General Hospital, Seoul, Korea
Corresponding Author: Jin-Wuk Hur ,Tel: +82-970-8672, Fax: +82-2-970-8672, Email: rheumatism@eulji.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/bync/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The systemic vasculitides are a group of diverse diseases characterized by blood vessel inflammation. The existing classification criteria are intended to create homogeneous patient groups for research and not to diagnose individual patients. However, they have been misused as diagnostic criteria, in both practice and research. The existing classification systems for vasculitis are limited by the overlapping features of disease entities and unrecognized pathogenic mechanisms. This review discusses the benefits and limitations of the widely used American College of Rheumatology criteria and Chapel Hill Consensus Conference nomenclature, updated in 2012. Improved diagnostics, including antineutrophil cytoplasmic antibody (ANCA) testing and imaging, argue for updating the established classification criteria. International efforts are underway to build a more effective classification and diagnostic criteria that reflect a better understanding of the pathophysiology of vasculitis and recent discoveries of genetics and biomarkers.
Keywords: Vasculitis; Classification criteria; Aanti-neutrophil cytoplasm antibody
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