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Korean J Med > Volume 87(2); 2014 > Article
The Korean Journal of Medicine 2014;87(2): 187-192.
췌장암과 감별하기 어려웠던 갑상선 유두암의 췌장 전이 1예
이지훈1, 이동기1, 장성일1, 최홍규1, 박찬익1, 윤지은2, 홍순원3
1연세대학교 의과대학 강남세브란스병원 내과
2한국생명공학연구원 바이오평가센터
3연세대학교 의과대학 강남세브란스병원 병리과
A Case of Pancreatic Metastasis From a Papillary Thyroid Carcinoma Mimicking Pancreatic Cancer
Ji Hoon Lee1, Dong Ki Lee1, Sung Ill Jang1, Hong Kyu Choi1, Chan Ik Park1, Ji Eun Yun2, Soon Won Hong3
1Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
2Department of Bioevaluation Center, Korea Research Institute of Bioscience and Biotechnology, Cheongwon, Korea
3Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Corresponding Author: Dong Ki Lee ,Tel: +82-2-2019-3214, Fax: +82-2-3463-3882, Email: dklee@yuhs.ac
Received: September 25, 2013;   Revised: October 14, 2013;   Accepted: December 19, 2013.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Papillary thyroid cancer (PTC) has a good prognosis and a low incidence of distant metastases. It is extremely rare for PTC to metastasize to the pancreas. Only five cases have been previously reported worldwide. Most cases are discovered incidentally by abdominal computed tomography (CT) or positron emission tomography-CT (PET-CT) during follow-up studies after thyroidectomies. Pancreatic metastasis of PTC is usually unidentifiable by a whole-body I131 scan, a common follow-up modality. When a pancreatic mass is found in patients with PTC, it must be differentiated from pancreatic cancer. In previous reports, patients with pancreatic metastases of PTC underwent operations for therapeutic diagnosis or underwent fine needle aspiration biopsies (FNAB). However, it is unclear whether the benefit of an operation outweighs the risk. We experienced a case of PTC with pancreatic metastasis that was found on PET-CT. Contrast-enhanced endoscopic ultrasonography (EUS) was performed to evaluate the characteristics of the pancreatic mass and pathological confirmation was obtained cytologically via EUS-FNA.
Keywords: Cancer of the thyroid; Pancreatic cancer; Fine-needle aspiration; Endoscopic ultrasonography
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