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Korean J Med > Volume 87(1); 2014 > Article
The Korean Journal of Medicine 2014;87(1): 92-95.
3, 4, 6번 뇌신경이 동시에 마비된 당뇨병성 다발성 뇌 신경병증 1예
반태현, 장상아, 이정민, 김지현, 김지혜, 노지웅, 김경훈
가톨릭대학교 의과대학 내과학교실
Case of Multiple Cranial Diabetic Neuropathies Involving the Third, Fourth and Sixth Cranial Nerves
Tae-Hyun Ban, Sang-Ah Chang, Jung-Min Lee, Ji-Hyun Kim, Ji-Hye Kim, Ji-Woong Roh, Kyung-Hoon Kim
Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea
Corresponding Author: Sang-Ah Chang ,Tel: +82-2-961-4510, Fax: +82-2-958-2398, Email: sangah@catholic.ac.kr
Received: November 13, 2013;   Accepted: February 20, 2014.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Multiple simultaneous cranial neuropathies occur rarely in diabetes patients. In general, diabetic cranial neuropathy presents in an isolated form and frequently involves oculomotor or facial nerves. We report a 73-year-old man with known type 2 diabetes mellitus who presented with severe dizziness, diplopia and third, fourth and sixth nerve ophthalmoplegia of both eyes. Radiological, laboratory and ophthalmic work-up including magnetic resonance imaging and angiography (MRI and MRA) revealed no specific tumor, aneurysm, or inflammation findings, except for a previous cerebral infarction and atherosclerotic changes in the internal carotid and vertebral arteries. After strict blood glucose control, the multiple cranial nerve palsies spontaneously resolved in 12 weeks. We report the case with a review of the literature.
Keywords: Cranial neuropathy; Diabetes mellitus; Ophthalmoplegia
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