| A Case of Life-Threatening Supraventricular Tachycardia Related to
Flecainide Toxicity |
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Sang Soo Cheon, Joon Hyuk Song, Myung Hwan Bae, Jang Hoon Lee, Dong Heon Yang, Hun Sik Park, Shung Chull Chae |
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Division of Cardiology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea |
| Flecainide 독성과 관련된 치명적인 심실상빈맥의 1예 |
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천상수, 송준혁, 배명환, 이장훈, 양동헌, 박헌식, 채성철 |
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경북대학교 의학전문대학원 내과학교실 순환기내과 |
Correspondence:
Dong Heon Yang, Tel: +82-53-420-6587, Fax: +82-53-426-2046, Email: ddhyang@knu.ac.kr
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Received: 11 July 2013 • Revised: 22 July 2013 • Accepted: 13 August 2013 |
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| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits
unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Abstract |
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Flecainide acetate is a potent class Ic anti-arrhythmic drug with a major sodium channel-blocking effect. Flecainide toxicity can
cause myocardial impairment and precipitate circulatory collapse, particularly in patients with renal failure. Electrical and hemodynamic
deterioration during flecainide toxicity may not respond to conventional treatments. We report the successful management of
flecainide toxicity using extracorporeal membrane oxygenation (ECMO), hemoperfusion, and bicarbonate administration maintaining
alkalinity. |
| Key Words:
Flecainide; Hemoperfusion; Extracorporeal membrane oxygenation |
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