Successful treatment of refractory livedoid vasculitis with rituximab and cyclophosphamide |
Eun Joo Song, Jong Wan Kang, Ji Hun Kim, Jin Young Kang, Eon Jeong Nam, Young Mo Kang |
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Rituximab과 cyclophosphamide 투여로 호전된 저항성 청피반성 혈관염 |
송은주, 강종완, 김지훈, 강진영, 남언정, 강영모 |
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Abstract |
Livedoid vasculitis (LV) is a chronic recurrent cutaneous disease that is characterized by a netlike vascular pattern of purpuric lesions that progress to ulcers and atrophic white scars. The etiology of LV is unknown. Various therapies have been used for LV with inconsistent results, including antiplatelet agents, fibrinolytics, anticoagulants, prostaglandin E1, and immunosuppressive agents, such as systemic corticosteroids, azathioprine, methotrexate, cyclosporine, and mycophenolate mofetil. We present a patient with idiopathic LV refractory to immunosuppressive therapy who had a good response to treatment with rituximab and cyclophosphamide. |
Key Words:
Livedoid vasculitis; Rituximab; Cyclophosphamide |
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