Korean J Med > Volume 78(1); 2010 > Article
The Korean Journal of Medicine 2010;78(1):87-94.
Association between nasogastric tube insertion and aspiration pneumonia in drug intoxication
Byoung Kwon Ghim, Sung Youn Choi, Im Ju Kang, Yoon Jung Kang, Bong Seok Kwon, Jae Eun Lee, Mi Hye Seo, Tae Houn Lee, Sung Keun Park
약물 중독에서 경비위관 거치와 흡인성 폐렴의 연관성
김병권, 최성연, 강임주, 강윤정, 권봉석, 이재은, 서미혜, 이태헌, 박성근
Abstract
Background/Aims: The clinical usefulness of nasogastric tube insertion in poisoning patients is controversial. This study compared the incidence of aspiration pneumonia between patients with or without nasogastric tubes. Methods: We retrospectively reviewed the clinical reports of poisoning patients seen from January 2006 to December 2007. We classified the patients into groups with and without nasogastric tube insertion and evaluated the incidence and risk factors of aspiration pneumonia. Results: Ultimately, 63 patients were included. The incidence of aspiration pneumonia was higher in patients with nasogastric tube insertion than in patients without nasogastric tube insertion (conscious patients: 58.8% vs. 11.8%, p=0.010; unconscious patients: 72.2% vs. 27.3%, p=0.027). Nasogastric tube insertion was a significant risk factor for developing aspiration pneumonia (odds ratio 3.54; 95% confidence interval 1.74~12.34). Conclusions: Nasogastric tube insertion did not prevent aspiration pneumonia, but was a risk factor. The results have implications in the development of a hypothesis about why a nasogastric tube increases the risk of aspiration pneumonia. This study has important limitations stemming mostly from other compounding factors and its retrospective design. (Korean J Med 78:87-94, 2010)
Key Words: Activated charcoal; Aspiration pneumonia; Nasogastric tube


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