Two patients with acquired hemophilia successfully treated with combination therapy including therapeutic plasmapheresis |
Eunkyung Park, Joung Soon Jang, Seonyang Park, Sang Jae Lee |
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치료적 혈장반출술을 포함한 병합요법으로 치료된 후천성 혈우병 2예 |
박은경·장정순·박선양·이상재, Joung Soon Jang, Seonyang Park, Sang Jae Lee |
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Abstract |
Acquired hemophilia is a rare disorder associated with fatal bleeding caused by the development of autoantibodies against factor
VIII. Here, we report the cases of two young women with acquired hemophilia who presented with massive internal hemorrhage
and purpura. Both patients were successfully treated with combination therapy including factor VIII or factor VIII bypassing agent,
immunosuppressants, and therapeutic plasmapheresis. (Korean J Med 77:367-370, 2009) |
Key Words:
Hemophilia A; Factor VIII; Autoantibodies; Plasmapheresis |
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