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The Korean Journal of Medicine 2009;77(3): 367-370.
치료적 혈장반출술을 포함한 병합요법으로 치료된 후천성 혈우병 2예
박은경·장정순·박선양·이상재, , ,
Two patients with acquired hemophilia successfully treated with combination therapy including therapeutic plasmapheresis
Eunkyung Park, Joung Soon Jang, Seonyang Park, Sang Jae Lee
ABSTRACT
Acquired hemophilia is a rare disorder associated with fatal bleeding caused by the development of autoantibodies against factor VIII. Here, we report the cases of two young women with acquired hemophilia who presented with massive internal hemorrhage and purpura. Both patients were successfully treated with combination therapy including factor VIII or factor VIII bypassing agent, immunosuppressants, and therapeutic plasmapheresis. (Korean J Med 77:367-370, 2009)
Keywords: Hemophilia A; Factor VIII; Autoantibodies; Plasmapheresis
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