Korean J Med > Volume 76(1); 2009 > Article
The Korean Journal of Medicine 2009;76(1):204-207.
Meningitis following vaccination with yellow-fever vaccine
Seong-Yeol Ryu, Young Ran Ju, Young Eui Jeong, M.S., Myung Guk Han, Nam Hi Ryoo
황열 백신 접종 후 발생한 뇌수막염 1예
류성열, 정영의, 주영란, 한명국, 류남희, Nam Hi Ryoo
Abstract
Yellow fever is the original viral hemorrhagic fever (VHF), a pansystemic viral sepsis with viremia, fever, prostration, hepatic, renal, and myocardial injury, hemorrhage, shock, and high lethality. Yellow fever was one of the most feared lethal diseases before the development of an effective vaccine. Yellow fever (YF) can be prevented by an attenuated vaccine. The yellow-fever 17D vaccine developed in the 1930s has been regarded as one of the most successful live attenuated vaccines, with few side effects or adverse events. The adverse effects associated with yellow-fever vaccine are generally mild and include headache, myalgia, and low-grade fever. Recently, however, some cases of severe neurologic disease and multi-organ system disease have been described in individuals who received yellow-fever vaccine. We report the case of a 39-year-old female with meningitis following vaccination with 17D yellow-fever vaccine. (Korean J Med 76:S204-S207, 2009)
Key Words: Yellow fever; Headache; Meningitis


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