| A case of acute Q fever with fibrin-ring granuloma in the bone marrow and lymph node biopsy |
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Oh Hyun Cho, Young Sill Choi, Tark Kim, Ki Ho Park, Ryan Oh, Hyun Sook Chi, Yang Soo Kim |
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| 골수 및 림프절생검에서 섬유소 고리 육아종 소견을 보인 급성 Q열 1예 |
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조오현, 최영실, 김 탁, 박기호, 오 련, 지현숙, 김양수 |
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| Abstract |
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Q fever is a zoonotic infection caused by Coxiella burnetii. Acute Q fever usually develops as a self-limited flu-like illness, atypical
pneumonia, or hepatitis. We experienced a case of Q fever in a 50-year-old male who had a prolonged fever. The bone marrow
and lymph node biopsy revealed fibrin-ring granulomas, which is a distinct finding of Q fever. The diagnosis was proven by high
titers of C. burnetii anti-phase II antibody (IgM 1:512 and IgG >1:2,048) and positive nested PCR for the com-1 gene. Q fever is
rare in Korea, but should be considered in the differential diagnosis of fever of unknown origin. (Korean J Med 76:S190-S194,
2009) |
| Key Words:
Q fever; Coxiella burnetii; Fibrin-ring granuloma |
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