A refractory chronic lymphocytic leukemia patient who responded to alemtuzumab |
Kyung Hee Kim, Moon Ki Choi, Jung Yong Hong, Young Eun Ha, Min Young Kim, Yoon Jung Kim, Won Seog Kim |
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증례 : Alemtuzumab에 반응을 보인 불응성 만성 림파구성 백혈병의 1예 |
김경희.최문기.홍정용.하영은.김민영.김윤정.김원석, Moon Ki Choi, Jung Yong Hong, Young Eun Ha, Min Young Kim, Yoon Jung Kim, Won Seog Kim |
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Abstract |
Chronic lymphocytic leukemia (CLL) has a relatively slow clinical course, but death is almost inevitable within a few years once the disease progresses. The prognosis in cases of CLL that become refractory to a previous chemotherapeutic agent is especially poor, and new modalities are needed to treat CLL. We experienced a case of chemorefractory CLL transformed from small lymphocytic lymphoma that responded to alemtuzumab. We report this case and review the literature. (Korean J Med 75:S823-S826, 2008) |
Key Words:
Chronic lymphocytic leukemia; Alemtuzumab |
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