Korean J Med > Volume 75(3); 2008 > Article
The Korean Journal of Medicine 2008;75(3):823-826.
A refractory chronic lymphocytic leukemia patient who responded to alemtuzumab
Kyung Hee Kim, Moon Ki Choi, Jung Yong Hong, Young Eun Ha, Min Young Kim, Yoon Jung Kim, Won Seog Kim
증례 : Alemtuzumab에 반응을 보인 불응성 만성 림파구성 백혈병의 1예
김경희.최문기.홍정용.하영은.김민영.김윤정.김원석, Moon Ki Choi, Jung Yong Hong, Young Eun Ha, Min Young Kim, Yoon Jung Kim, Won Seog Kim
Abstract
Chronic lymphocytic leukemia (CLL) has a relatively slow clinical course, but death is almost inevitable within a few years once the disease progresses. The prognosis in cases of CLL that become refractory to a previous chemotherapeutic agent is especially poor, and new modalities are needed to treat CLL. We experienced a case of chemorefractory CLL transformed from small lymphocytic lymphoma that responded to alemtuzumab. We report this case and review the literature. (Korean J Med 75:S823-S826, 2008)
Key Words: Chronic lymphocytic leukemia; Alemtuzumab


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