| Successful allogeneic hematopoietic stem cell transplantation in a refractory acute myelogenous leukemia (AML) patient with hepatosplenic candidiasis |
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Dae-Jun Kim, Woong-Ryong Jung, Shin-Ae Park, Si-Hyun Kim, Hee-Je Kim, Woo-Sung Min, Chun-Choo Kim |
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경희대학교 의과대학 순환기내과학교실 |
| 증례 : 간비장 칸디다증이 동반된 급성백혈병 환자에서의 동종 조혈모세포이식 |
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김대준, 정웅룡, 박신애, 김시현, 김희제, 민우성, 김춘추 |
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| Abstract |
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Hepatosplenic candidiasis is a form of disseminated fungal infection mainly involving the liver, spleen, and occasionally the kidneys. Because most patients are in remission at the time of diagnosis of hepatosplenic candidiasis, the usual dilemma is whether to delay further chemotherapy or hematopoietic stem cell transplantation, or to hold further treatment until the infection is completely eradicated. We report a 37-year-old man with acute myelogenous leukemia (AML) who developed hepatosplenic candidiasis after reinduction chemotherapy. Moreover, he was not in complete remission at that time of infection. He was supposed to receive an allogeneic hematopoietic stem cell transplantation simultaneously with amphotericin B prophylaxis. Due to intensive supportive care and infection control with anti-fungal prophylaxis, he successfully completed the transplant procedure without reactivation of hepatosplenic candidiasis. |
| Key Words:
Acute myelogenous leukemia; Hepatosplenic candidiasis; Hematopoietic stem cell transplantation; Amphotericin B |
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