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The Korean Journal of Medicine 2008;74(2): 203-207.
증례 : 내과적 치료에 반응하지 않은 Lemierre 증후군 1예
허태윤 . 정복현 . 유내선 . 정형주 . 조민형 . 김미혜 . 류대식, Bock Hyun Jung, Nae Sun Ryou, Hyoung Chu Joung, Min Hyung Cho, Mi Hye Kim, Dae Sik Ryu
A case of lemierre syndrome poorly responsive to medical treatment
Tae Yun Heo, Bock Hyun Jung, Nae Sun Ryou, Hyoung Chu Joung, Min Hyung Cho, Mi Hye Kim, Dae Sik Ryu
경희대학교 의과대학 순환기내과학교실
Lemierre syndrome is a rare clinical condition that is characterized by anaerobic oropharyngeal infections leading to septic thrombophlebitis of the internal jugular vein and frequent secondary metastatic infections. The accurate diagnosis and treatment, for early stage disease, is important because it may be associated with a high mortality rate if untreated. We present the case of a 34-year-old man who presented with a history of typical for the diagnosis of Lemierre syndrome. Supportive care with antibiotics did not improve the clinical condition. The clinical course improved after treatment with IV anticoagulant and surgical thrombectomy. In addition, he had the antiphospholipid syndrome, which is known to be a common cause of acquired arterial or venous thrombosis. Therefore, in this patient the associated antiphospholipid syndrome might precipitate an internal jugular venous thrombophlebitis after an oropharyngeal infection or might account for the poor response to medical treatment.
Keywords: Lemierre syndrome; Pneumonia; Empyema; Thrombophlebitis; Antiphospholipid syndrome
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