| Adolescents and young adults (AYA) with acute lymphoblastic leukemia |
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Hyeoung-Joon Kim |
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한림대학교 의과대학 내과학교실 강동성심병원 심혈관센터 |
| 종설 : 청소년 급성림프구성백혈병 |
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김 형 준 |
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| Abstract |
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Adolescents and young adults (AYA) with acute lymphoblastic leukemia (ALL) constitute a distinct population from
children and older adults. However, AYA represent a minority of patients enrolled onto either adult or pediatric clinical
trials. As a result, little information is available regarding complete remission (CR), event-free survival (EFS) and
overall survival (OS) rates for this age group, and the appropriate treatment regimen for this group of patients remains
elusive. A systematic review of all published clinical trials, which provide data on treatment and outcome of AYA with
ALL, has been summarized in an effort to determine whether they should be treated on pediatric or adult protocols. AYA
with ALL have far superior outcomes when treated on more intensive pediatric regimens and are required specific
collaborative trials in order to optimize and improved outcomes.(Korean J Med 73:459-463, 2007) |
| Key Words:
Adolescents and young adults (AYA), Acute lymphoblastic leukemia (ALL) |
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