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Primary hyperaldosteronism is an uncommon cause of hypertension which classically features hypokalemia, metabolic alkalosis and excessive urinary potassium excretion. Clinical manifestations of hypokalemia rarely reveal the diagnosis. We report a case of hypertensive patient who developed periodic paralysis and rhabdomyolysis induced by a severe hypokalemia. Clinical manifestations were reversible after potassium supplementation. Laboratory and radiological findings led to the diagnosis of an aldosterone-producing adenoma. Surgical treatment allowed correction of electrolyte abnormalities and improvement of hypertension.(Korean J Med 70:S261-S266, 2006)
Key Words : Primary aldosteronism, Periodic paralysis, Rhabdomyolysis |
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