| Home | E-Submission | Sitemap | Contact Us
Korean J Med > Volume 86(5); 2014 > Article
The Korean Journal of Medicine 2014;86(5): 557-562.
Treatment of Severe Sepsis-Surviving Sepsis Campaign Guideline쓣 以묒떖쑝濡
꽌슱븰援 쓽怨쇰븰 궡怨쇳븰援먯떎
Treatment of Severe Sepsis-Based on Surviving Sepsis Campaign Guideline
Sang-Min Lee
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Sang-Min Lee ,Tel: +82-2-2072-0833, Fax: +82-2-762-9662, Email: sangmin2@snu.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Share :  
Sepsis is a systemic, deleterious host response to infection. The term 쐓evere sepsis is used when sepsis is complicated by acute organ dysfunction, and "septic shock" as sepsis complicated by either hypotension that is refractory to fluid resuscitation or by hyperlactatemia. The number of cases with severe sepsis exceeds 750,000 per year in the United States and the mortality is now closer to 20 to 30% in these days. The principles of the initial management bundle are to provide sufficient hemodynamic resuscitation and early initiation of appropriate antibiotics to mitigate uncontrolled infection. Initial resuscitation requires the use of intravenous fluids and vasopressors. It is very important to achieve the target of initial resuscitation. The supportive cares in ICU are also significant such as blood component transfusion, glucose control, renal replacement therapy, deep vein thrombosis prophylaxis and stress ulcer prophylaxis. The goals of care and prognosis including end-of-life care should be discussed with patients and families as early as feasible. (Korean J Med 2014;86:557-562)
Keywords: Sepsis; Severe sepsis; Septic shock; Guidelines; Evidence-based medicine; Sepsis bundles
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Supplementary Material  Supplementary Material
Editorial Office
101-2501, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-793-4364, 4311   Fax: +82-2-790-0993    E-mail: kaim@kams.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © The Korean Association of Internal Medicine. All rights reserved.                powerd by m2community